Henrik Hagberg Selected Research

Brain Injuries (Brain Injury)

10/2021	White matter injury but not germinal matrix hemorrhage induces elevated osteopontin expression in human preterm brains.
10/2021	Therapies for neonatal encephalopathy: Targeting the latent, secondary and tertiary phases of evolving brain injury.
1/2021	N-Acetyl Cysteine Restores Sirtuin-6 and Decreases HMGB1 Release Following Lipopolysaccharide-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Mice.
1/2021	Neuroprotection offered by mesenchymal stem cells in perinatal brain injury: Role of mitochondria, inflammation, and reactive oxygen species.
1/2021	Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse brain.
1/2020	Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.
1/2020	Inhibiting the interaction between apoptosis-inducing factor and cyclophilin A prevents brain injury in neonatal mice after hypoxia-ischemia.
1/2020	A Model of Germinal Matrix Hemorrhage in Preterm Rat Pups.
1/2019	Magnesium induces preconditioning of the neonatal brain via profound mitochondrial protection.
1/2019	The Role of Mitochondrial and Endoplasmic Reticulum Reactive Oxygen Species Production in Models of Perinatal Brain Injury.

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Henrik Hagberg Research Topics

Disease

59	Brain Injuries (Brain Injury) 10/2021 - 01/2002
55	Hypoxia (Hypoxemia) 01/2021 - 01/2002
44	Ischemia 01/2021 - 04/2002
36	Inflammation (Inflammations) 01/2022 - 06/2003
13	Premature Obstetric Labor (Premature Labor) 01/2019 - 02/2003
11	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 03/2022 - 07/2003
9	Asphyxia (Suffocation) 01/2021 - 01/2006
9	Infections 01/2020 - 06/2002
9	Rupture 01/2013 - 05/2003
8	Premature Birth (Birth, Premature) 04/2015 - 02/2003
7	Brain Diseases (Brain Disorder) 01/2022 - 01/2012
6	Cerebral Palsy (Spastic Diplegia) 01/2022 - 04/2003
6	Gliosis 01/2022 - 01/2007
5	Neuroinflammatory Diseases 10/2021 - 03/2014
5	Necrosis 01/2020 - 01/2002
4	Hypothermia 10/2018 - 10/2003
4	Brain Ischemia (Cerebral Ischemia) 02/2007 - 04/2002
3	Hemorrhage 01/2022 - 01/2020
3	Pre-Eclampsia (Preeclampsia) 10/2019 - 02/2015
3	Fetal Growth Retardation (Intrauterine Growth Retardation) 11/2011 - 02/2002
3	Paralysis (Palsy) 12/2008 - 06/2002
3	Infarction (Infarctions) 06/2004 - 07/2002
2	Cognitive Dysfunction 01/2021 - 01/2017
2	Body Weight (Weight, Body) 01/2020 - 08/2011
2	Type 2 Diabetes Mellitus (MODY) 01/2020 - 10/2018
2	Stroke (Strokes) 01/2015 - 01/2007
2	Preterm Premature Rupture of the Membranes 08/2012 - 12/2007
2	Birth Weight (Birth Weights) 06/2008 - 11/2005
2	Pelvic Girdle Pain 06/2008 - 04/2005
2	Chorioamnionitis 12/2007 - 06/2002
2	Shoulder Dystocia 11/2005 - 07/2005
2	Hypoglycemia (Reactive Hypoglycemia) 01/2004 - 01/2002
1	Hematoma 01/2021

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 10/2021 - 08/2004
17	LipopolysaccharidesIBA 01/2021 - 02/2003
13	CytokinesIBA 01/2021 - 01/2002
12	Caspase 3 (Caspase-3)IBA 01/2022 - 01/2002
11	Neuroprotective AgentsIBA 01/2020 - 01/2002
10	CaspasesIBA 01/2020 - 01/2002
9	Interleukin-6 (Interleukin 6)IBA 01/2013 - 01/2002
8	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2005
8	Apoptosis Inducing FactorIBA 01/2020 - 07/2003
7	Messenger RNA (mRNA)IBA 01/2021 - 01/2002
7	Peptides (Polypeptides)IBA 01/2021 - 09/2010
7	Oxygen (Dioxygen)IBA 01/2020 - 10/2003
7	Interleukin-18 (Interleukin 18)IBA 01/2013 - 07/2002
6	Interleukin-8 (Interleukin 8)IBA 12/2007 - 02/2002
6	InterleukinsIBA 09/2006 - 01/2002
4	Phosphates (Orthophosphate)IBA 01/2017 - 10/2003
4	Cytochromes c (Cytochrome c)IBA 01/2016 - 04/2002
4	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 01/2004
4	Insulin-Like Growth Factor I (IGF-1)IBA 08/2011 - 01/2002
3	ChemokinesIBA 01/2021 - 03/2005
3	Interleukin-10 (Interleukin 10)IBA 01/2021 - 02/2002
3	AntioxidantsIBA 01/2021 - 12/2007
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 07/2008
3	Complement System Proteins (Complement)IBA 01/2021 - 09/2013
3	Free RadicalsIBA 12/2018 - 02/2006
3	Pharmaceutical PreparationsIBA 10/2018 - 01/2007
3	CalciumIBA 12/2015 - 02/2004
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2014 - 01/2002
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2009 - 07/2004
2	Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric 01/2022 - 10/2019
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	OsteopontinIBA 10/2021 - 12/2014
2	IronIBA 01/2020 - 10/2003
2	Glutamic Acid (Glutamate)FDA Link 01/2020 - 06/2002
2	Acetylcysteine (Siran)FDA LinkGeneric 01/2020 - 03/2007
2	Cyclophilin AIBA 01/2020 - 08/2007
2	MagnesiumIBA 01/2019 - 11/2018
2	Protein Isoforms (Isoforms)IBA 12/2018 - 03/2005
2	Phosphotransferases (Kinase)IBA 01/2017 - 01/2009
2	Glycogen Synthase (Synthase I)IBA 01/2016 - 11/2005
2	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2015 - 12/2009
2	Transcription Factors (Transcription Factor)IBA 09/2015 - 09/2014
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 09/2015 - 05/2014
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2015 - 12/2004
2	NF-kappa B (NF-kB)IBA 01/2015 - 06/2007
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2013 - 10/2003
2	Caspase 2IBA 05/2012 - 11/2011
2	Protein Kinases (Protein Kinase)IBA 04/2012 - 11/2005
2	Matrix Metalloproteinases (MMPs)IBA 01/2012 - 02/2007
2	Excitatory Amino AcidsIBA 09/2009 - 12/2004
2	Insulin (Novolin)FDA Link 09/2009 - 01/2002
2	MelatoninIBA 03/2007 - 02/2007
2	Interleukin-1 (Interleukin 1)IBA 09/2006 - 03/2005
2	EndotoxinsIBA 01/2006 - 01/2006
2	salicylhydroxamic acid (SHAM)IBA 02/2005 - 10/2003
2	OligonucleotidesIBA 12/2004 - 12/2004
2	Transforming Growth Factor beta (TGF-beta)IBA 02/2002 - 01/2002
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 01/2022
1	CholesterolIBA 01/2022
1	Sulfhydryl Compounds (Thiols)IBA 01/2021

Therapy/Procedure

12	Ligation 01/2020 - 07/2003
11	Therapeutics 10/2021 - 07/2010
8	Induced Hypothermia 03/2022 - 12/2015
3	Traction 12/2008 - 11/2005
2	Intranasal Administration 01/2021 - 01/2017
2	Aftercare (After-Treatment) 01/2016 - 04/2005
2	Epidural Anesthesia 11/2005 - 07/2005